Neuropeptide Y-immunoreactive synapses in the intermediolateral cell column of rat and rabbit thoracic spinal cord

I. J. Llewellyn-Smith, J. B. Minson, David A Morilak, J. R. Oliver, J. P. Chalmers

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Neuropeptide Y (NPY)-immunoreactive nerve fibers in the intermediolateral cell column of rat spinal cord segments T2-T3 and T8-T10 and rabbit segments T3-T6 were studied with light and electron microscopic immunocytochemistry. Plexuses of NPY-immunoreactive nerve fibers were found by light microscopy. NPY-positive synapses were present electron microscopically but non-immunoreactive synapses greatly outnumbered NPY-immunoreactive ones. In the lateral horn of rat T9, 30% of the vesicle-containing NPY-positive axon profiles formed synapses, 95% of which were axodendritic. These synaptic connections may mediate the effects of brainstem NPY neurons on the activity of sympathetic preganglionic neurons.

Original languageEnglish (US)
Pages (from-to)243-248
Number of pages6
JournalNeuroscience Letters
Volume108
Issue number3
DOIs
StatePublished - Jan 22 1990
Externally publishedYes

Fingerprint

Neuropeptide Y
Synapses
Spinal Cord
Thorax
Rabbits
Nerve Fibers
Electrons
Neurons
Light
Horns
Brain Stem
Axons
Spinal Cord Lateral Horn
Microscopy
Immunohistochemistry

Keywords

  • Blood pressure
  • Immunocytochemistry
  • Intermediolateral cell column
  • Neuropeptide Y
  • Spinal cord
  • Ultrastructure

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Neuropeptide Y-immunoreactive synapses in the intermediolateral cell column of rat and rabbit thoracic spinal cord. / Llewellyn-Smith, I. J.; Minson, J. B.; Morilak, David A; Oliver, J. R.; Chalmers, J. P.

In: Neuroscience Letters, Vol. 108, No. 3, 22.01.1990, p. 243-248.

Research output: Contribution to journalArticle

Llewellyn-Smith, I. J. ; Minson, J. B. ; Morilak, David A ; Oliver, J. R. ; Chalmers, J. P. / Neuropeptide Y-immunoreactive synapses in the intermediolateral cell column of rat and rabbit thoracic spinal cord. In: Neuroscience Letters. 1990 ; Vol. 108, No. 3. pp. 243-248.
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