Neurologic Manifestations of Systemic Lupus Erythematosus in Children and Adults

Eyal Muscal, Robin L. Brey

Research output: Contribution to journalReview articlepeer-review

134 Scopus citations


Among the collagen vascular diseases neurologic manifestations have been most commonly recognized and well-studied in systemic lupus erythematosus (SLE, lupus). Neurologic manifestations are less prevalent in other systemic inflammatory and autoimmune disorders. This review focuses on the clinical presentation, pathophysiology, and treatment strategies of neuropsychiatric lupus (NPSLE) in children and adults.

Original languageEnglish (US)
Pages (from-to)61-73
Number of pages13
JournalNeurologic Clinics
Issue number1
StatePublished - Feb 2010


  • Autoantibodies
  • Cognitive dysfunction
  • Collagen vascular disease
  • Neurologic disease
  • Systemic lupus erythematosus

ASJC Scopus subject areas

  • Clinical Neurology


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