Neuroimmunology: Clinical and therapeutic approach

Robin L. Brey, Richard J. Barohn, Joseph A. Tami

Research output: Contribution to journalArticlepeer-review


BACKGROUND- The purpose of this review is to provide information about immune-mediated diseases of the nervous system in a way that is clinically useful and that emphasizes current therapeutic approaches. REVIEW SUMMARY- Advances in our understanding of immune system functioning that are relevant to the pathogenesis of individual diseases or treatment mechanisms are provided. Therapeutic modalities that are used to treat many immune-mediated disorders are discussed. Clinical, immunological, and treatment aspects of specific major immune-mediated disorders of the nervous system are discussed. CONCLUSION- Major advances have been made in the last few years that further our understanding of both normal and pathogenetic immune system functioning within the central nervous system. These basic advances have underscored the development of new effective and specific treatment options that now exist for immune-mediated nervous system diseases such as multiple sclerosis.

Original languageEnglish (US)
Pages (from-to)25-52
Number of pages28
Issue number1
StatePublished - Jan 1 1996


  • Antiphospholipid antibodies
  • Chronic inflammatory polyradiculoneuropathy
  • Guillain-Barré syndrome
  • Multiple sclerosis
  • Myasthenia gravis
  • Neuroimmunology
  • Paraneoplastic disorders
  • Vasculitis

ASJC Scopus subject areas

  • Clinical Neurology


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