Neuroendocrinological approach for examining the mechanisms of action of Toki‐Shakuyaku‐San (TJ‐23) on the activity of tyrosine hydroxylase in the brain

Kazuo Toriizuka; Nobuyoshi Hagino; Katsutoshi Terasawa

doi:10.1002/ptr.2650070721

Neuroendocrinological approach for examining the mechanisms of action of Toki‐Shakuyaku‐San (TJ‐23) on the activity of tyrosine hydroxylase in the brain

Kazuo Toriizuka, Nobuyoshi Hagino, Katsutoshi Terasawa

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Administration of the Kampo medicine, TJ‐23, to ovariectomized rats resulted in decreased tyrosis hydroxylase (TH) activity in the dorsal hippocampus but an increased activity in the ventral tegmental area. A decrease of TH activity in the hypothalamus was not statistically significant. The effect of TJ‐23 was compared to oestrogen in a similar group of rats and it was concluded that the standard drug and TJ‐23 induced similar effects.

Original language	English (US)
Pages (from-to)	S70-S72
Journal	Phytotherapy Research
Volume	7
Issue number	7
DOIs	https://doi.org/10.1002/ptr.2650070721
State	Published - 1993
Externally published	Yes

Keywords

brain tyrosine hydroxylase
Kampo medicines
rats

ASJC Scopus subject areas

Pharmacology

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10.1002/ptr.2650070721

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abstract = "Administration of the Kampo medicine, TJ‐23, to ovariectomized rats resulted in decreased tyrosis hydroxylase (TH) activity in the dorsal hippocampus but an increased activity in the ventral tegmental area. A decrease of TH activity in the hypothalamus was not statistically significant. The effect of TJ‐23 was compared to oestrogen in a similar group of rats and it was concluded that the standard drug and TJ‐23 induced similar effects.",

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AU - Toriizuka, Kazuo

AU - Hagino, Nobuyoshi

AU - Terasawa, Katsutoshi

PY - 1993

Y1 - 1993

N2 - Administration of the Kampo medicine, TJ‐23, to ovariectomized rats resulted in decreased tyrosis hydroxylase (TH) activity in the dorsal hippocampus but an increased activity in the ventral tegmental area. A decrease of TH activity in the hypothalamus was not statistically significant. The effect of TJ‐23 was compared to oestrogen in a similar group of rats and it was concluded that the standard drug and TJ‐23 induced similar effects.

AB - Administration of the Kampo medicine, TJ‐23, to ovariectomized rats resulted in decreased tyrosis hydroxylase (TH) activity in the dorsal hippocampus but an increased activity in the ventral tegmental area. A decrease of TH activity in the hypothalamus was not statistically significant. The effect of TJ‐23 was compared to oestrogen in a similar group of rats and it was concluded that the standard drug and TJ‐23 induced similar effects.

KW - brain tyrosine hydroxylase

KW - Kampo medicines

KW - rats

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Neuroendocrinological approach for examining the mechanisms of action of Toki‐Shakuyaku‐San (TJ‐23) on the activity of tyrosine hydroxylase in the brain

Abstract

Keywords

ASJC Scopus subject areas

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