Abstract
Nonsteroidal anti-inflammatory drugs (NSAIDs) are important therapeutic agents in the management of rheumatologic disorders and other pain syndromes. Over the counter availability of the drugs has expanded the usage of the drugs. This article reviews the nephrotoxicity of these drugs, with some emphasis on NSAID-related proteinuria. Although reversibility of renal involvement upon drug discontinuance is the rule, progression to end-stage renal disease has occurred. A proposed guideline for monitoring renal impairment in low- and high-risk patients is also presented.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 187-192 |
| Number of pages | 6 |
| Journal | Mineral and Electrolyte Metabolism |
| Volume | 20 |
| Issue number | 4 |
| State | Published - 1994 |
Keywords
- NSAIDs
- Nephrotoxicity
- Prostaglandins
- Proteinuria
- Renal failure
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Biochemistry