Nephrotoxicity from Nonsteroidal Anti-Inflammatory Drugs

W. Brian Reeves; Richard J. Foley; Edward J. Weinman

doi:10.1097/00007611-198503000-00021

Nephrotoxicity from Nonsteroidal Anti-Inflammatory Drugs

W. Brian Reeves, Richard J. Foley, Edward J. Weinman

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

We categorize the three types of renal dysfunction associated with the use of nonsteroidal anti-inflammatory drugs (NSAID): Acute renal failure, acute interstitial nephritis, and hyperkalemia. The paper provides clinical examples of each type, discusses pathophysiology, and describes response to therapy, in addition to outlining the usefulness of labeled leukocyte nuclear studies and kidney biopsy. We conclude that these drugs are relatively common causes of renal dysfunction, particularly in selected subpopulations.

Original language	English (US)
Pages (from-to)	318-322
Number of pages	5
Journal	Southern medical journal
Volume	78
Issue number	3
DOIs	https://doi.org/10.1097/00007611-198503000-00021
State	Published - Mar 1985
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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10.1097/00007611-198503000-00021

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abstract = "We categorize the three types of renal dysfunction associated with the use of nonsteroidal anti-inflammatory drugs (NSAID): Acute renal failure, acute interstitial nephritis, and hyperkalemia. The paper provides clinical examples of each type, discusses pathophysiology, and describes response to therapy, in addition to outlining the usefulness of labeled leukocyte nuclear studies and kidney biopsy. We conclude that these drugs are relatively common causes of renal dysfunction, particularly in selected subpopulations.",

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AU - Foley, Richard J.

AU - Weinman, Edward J.

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N2 - We categorize the three types of renal dysfunction associated with the use of nonsteroidal anti-inflammatory drugs (NSAID): Acute renal failure, acute interstitial nephritis, and hyperkalemia. The paper provides clinical examples of each type, discusses pathophysiology, and describes response to therapy, in addition to outlining the usefulness of labeled leukocyte nuclear studies and kidney biopsy. We conclude that these drugs are relatively common causes of renal dysfunction, particularly in selected subpopulations.

AB - We categorize the three types of renal dysfunction associated with the use of nonsteroidal anti-inflammatory drugs (NSAID): Acute renal failure, acute interstitial nephritis, and hyperkalemia. The paper provides clinical examples of each type, discusses pathophysiology, and describes response to therapy, in addition to outlining the usefulness of labeled leukocyte nuclear studies and kidney biopsy. We conclude that these drugs are relatively common causes of renal dysfunction, particularly in selected subpopulations.

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Nephrotoxicity from Nonsteroidal Anti-Inflammatory Drugs

Abstract

ASJC Scopus subject areas

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