Nephropathy in youth and young adults with type 2 diabetes topical collection on pediatric type 2 diabetes

Carolina Solis-Herrera, Curtis L. Triplitt, Jane L. Lynch

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

The occurrence and progression of nephropathy associated with early onset type 2 diabetes (T2D) is a consequence of the ongoing epidemic of childhood obesity. Minimal evidence regarding treatment effectiveness of renovascular comorbidities in youth with early onset T2D is available, due to the relatively recent emergence of T2D in youth and young adults. Extrapolation of adult therapy guidelines is not an ideal approach to making therapeutic decisions in this population. Evolving management and intervention strategies are based on accumulating longitudinal data from cohorts of well characterized youth and young adults with T2D. The degree of similarity in histologic findings and disease specific characteristics of kidney disease in patients with early onset T2D and albuminuria compared with affected adults is not well characterized. Early aggressive therapies to minimize the impact of nephropathy are indicated as the evidence for best therapies in youth with T2D are further explored.

Original languageEnglish (US)
Article number456
JournalCurrent Diabetes Reports
Volume14
Issue number2
DOIs
StatePublished - Feb 2014

Keywords

  • Microalbuminuria
  • Nephropathy
  • Type 2 diabetes
  • Young adults
  • Youth

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism

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