Nephrogenic systemic fibrosis/nephrogenic fibrosing dermopathy: A primer for radiologists

Srinivasa R. Prasad, Jaishree Jagirdar

Research output: Contribution to journalReview article

16 Scopus citations

Abstract

Nephrogenic systemic fibrosis (NSF) is a rare, idiopathic systemic fibrosing disorder that is predominantly characterized by a clinicopathologically distinct symmetric dermopathy and debilitating joint contractures. The condition affects patients with renal insufficiency and appears to show improvement with prompt restoration of renal function. Although NSF was initially reported in the United States as nephrogenic fibrosing dermopathy, it has subsequently been described in patients in Europe and Asia. More than 215 cases of NSF have been reported in the nephrogenic fibrosing dermopathy/NSF registry that is currently maintained at the Yale University. Recent reports suggest a possible etiologic link between systemic administration of gadolinium-containing magnetic resonance imaging contrast agents in patients with renal insufficiency and the development of NSF.

Original languageEnglish (US)
Pages (from-to)1-3
Number of pages3
JournalJournal of Computer Assisted Tomography
Volume32
Issue number1
DOIs
StatePublished - Jan 1 2008

Keywords

  • Gadolinium
  • MRI
  • Renal failure
  • Systemic fibrosis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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