Neonatal lead intoxication following maternal pica: A case report and review of the literature

Margarita Vasquez; Victor F. German; Anthony A. Scott; D. Michael Foulds; Cynthia Blanco

doi:10.3233/NPM-2009-0058

Neonatal lead intoxication following maternal pica: A case report and review of the literature

Margarita Vasquez, Victor F. German, Anthony A. Scott, D. Michael Foulds, Cynthia Blanco

Department of Pediatrics

Research output: Contribution to journal › Article › peer-review

Abstract

Pica is a significant risk factor for lead exposure during pregnancy and may often go unrecognized. Lead exposure in the pregnant woman may be extremely toxic to the fetus due to unencumbered transport across the placenta. Long term neurological effects of in utero and neonatal lead exposure are largely unknown, and the efficacies of current therapies are controversial. We report a case of a pregnant woman with elevated blood lead levels secondary to pica that was not identified by a routine screening survey. Her full term baby girl had a blood lead level of 70.8 µg/dL. Neonatal therapy with double-volume exchange transfusion followed by a 3 day course of intravenous Edetate Calcium Disodium is described as well as the slow steady decline of her blood lead levels. Neurocognitive development to 18 months is also reported.

Original language	English (US)
Pages (from-to)	123-126
Number of pages	4
Journal	Journal of Neonatal-Perinatal Medicine
Volume	2
Issue number	2
DOIs	https://doi.org/10.3233/NPM-2009-0058
State	Published - 2009

Keywords

Chelation
Lead
Neonate

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

Access to Document

10.3233/NPM-2009-0058

Cite this

@article{762bdc018ae94b76b6dd1a32e8de5229,

title = "Neonatal lead intoxication following maternal pica: A case report and review of the literature",

abstract = "Pica is a significant risk factor for lead exposure during pregnancy and may often go unrecognized. Lead exposure in the pregnant woman may be extremely toxic to the fetus due to unencumbered transport across the placenta. Long term neurological effects of in utero and neonatal lead exposure are largely unknown, and the efficacies of current therapies are controversial. We report a case of a pregnant woman with elevated blood lead levels secondary to pica that was not identified by a routine screening survey. Her full term baby girl had a blood lead level of 70.8 µg/dL. Neonatal therapy with double-volume exchange transfusion followed by a 3 day course of intravenous Edetate Calcium Disodium is described as well as the slow steady decline of her blood lead levels. Neurocognitive development to 18 months is also reported.",

keywords = "Chelation, Lead, Neonate",

author = "Margarita Vasquez and German, {Victor F.} and Scott, {Anthony A.} and {Michael Foulds}, D. and Cynthia Blanco",

year = "2009",

doi = "10.3233/NPM-2009-0058",

language = "English (US)",

volume = "2",

pages = "123--126",

journal = "Journal of Neonatal-Perinatal Medicine",

issn = "1934-5798",

publisher = "IOS Press",

number = "2",

}

TY - JOUR

T1 - Neonatal lead intoxication following maternal pica

T2 - A case report and review of the literature

AU - Vasquez, Margarita

AU - German, Victor F.

AU - Scott, Anthony A.

AU - Michael Foulds, D.

AU - Blanco, Cynthia

PY - 2009

Y1 - 2009

N2 - Pica is a significant risk factor for lead exposure during pregnancy and may often go unrecognized. Lead exposure in the pregnant woman may be extremely toxic to the fetus due to unencumbered transport across the placenta. Long term neurological effects of in utero and neonatal lead exposure are largely unknown, and the efficacies of current therapies are controversial. We report a case of a pregnant woman with elevated blood lead levels secondary to pica that was not identified by a routine screening survey. Her full term baby girl had a blood lead level of 70.8 µg/dL. Neonatal therapy with double-volume exchange transfusion followed by a 3 day course of intravenous Edetate Calcium Disodium is described as well as the slow steady decline of her blood lead levels. Neurocognitive development to 18 months is also reported.

AB - Pica is a significant risk factor for lead exposure during pregnancy and may often go unrecognized. Lead exposure in the pregnant woman may be extremely toxic to the fetus due to unencumbered transport across the placenta. Long term neurological effects of in utero and neonatal lead exposure are largely unknown, and the efficacies of current therapies are controversial. We report a case of a pregnant woman with elevated blood lead levels secondary to pica that was not identified by a routine screening survey. Her full term baby girl had a blood lead level of 70.8 µg/dL. Neonatal therapy with double-volume exchange transfusion followed by a 3 day course of intravenous Edetate Calcium Disodium is described as well as the slow steady decline of her blood lead levels. Neurocognitive development to 18 months is also reported.

KW - Chelation

KW - Lead

KW - Neonate

UR - http://www.scopus.com/inward/record.url?scp=85013583505&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85013583505&partnerID=8YFLogxK

U2 - 10.3233/NPM-2009-0058

DO - 10.3233/NPM-2009-0058

M3 - Article

AN - SCOPUS:85013583505

VL - 2

SP - 123

EP - 126

JO - Journal of Neonatal-Perinatal Medicine

JF - Journal of Neonatal-Perinatal Medicine

SN - 1934-5798

IS - 2

ER -

Neonatal lead intoxication following maternal pica: A case report and review of the literature

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this