Neonatal lead intoxication following maternal pica: A case report and review of the literature

Margarita Vasquez; Victor F. German; Anthony A. Scott; D. Michael Foulds; Cynthia Blanco

doi:10.3233/NPM-2009-0058

Neonatal lead intoxication following maternal pica: A case report and review of the literature

Margarita Vasquez, Victor F. German, Anthony A. Scott, D. Michael Foulds, Cynthia Blanco

Pediatrics

Research output: Contribution to journal › Article › peer-review

Abstract

Pica is a significant risk factor for lead exposure during pregnancy and may often go unrecognized. Lead exposure in the pregnant woman may be extremely toxic to the fetus due to unencumbered transport across the placenta. Long term neurological effects of in utero and neonatal lead exposure are largely unknown, and the efficacies of current therapies are controversial. We report a case of a pregnant woman with elevated blood lead levels secondary to pica that was not identified by a routine screening survey. Her full term baby girl had a blood lead level of 70.8 µg/dL. Neonatal therapy with double-volume exchange transfusion followed by a 3 day course of intravenous Edetate Calcium Disodium is described as well as the slow steady decline of her blood lead levels. Neurocognitive development to 18 months is also reported.

Original language	English (US)
Pages (from-to)	123-126
Number of pages	4
Journal	Journal of Neonatal-Perinatal Medicine
Volume	2
Issue number	2
DOIs	https://doi.org/10.3233/NPM-2009-0058
State	Published - 2009

Keywords

Chelation
Lead
Neonate

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.3233/NPM-2009-0058

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abstract = "Pica is a significant risk factor for lead exposure during pregnancy and may often go unrecognized. Lead exposure in the pregnant woman may be extremely toxic to the fetus due to unencumbered transport across the placenta. Long term neurological effects of in utero and neonatal lead exposure are largely unknown, and the efficacies of current therapies are controversial. We report a case of a pregnant woman with elevated blood lead levels secondary to pica that was not identified by a routine screening survey. Her full term baby girl had a blood lead level of 70.8 µg/dL. Neonatal therapy with double-volume exchange transfusion followed by a 3 day course of intravenous Edetate Calcium Disodium is described as well as the slow steady decline of her blood lead levels. Neurocognitive development to 18 months is also reported.",

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