Natural pathology of the captive chimpanzee (Pan troglodytes): A 35-year review

Shyamesh Kumar, Hannah Laurence, Michael A. Owston, R. Mark Sharp, Priscilla Williams, Robert E. Lanford, Gene B. Hubbard, Edward J. Dick

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations

Abstract

We present the spontaneous pathological lesions identified as a result of necropsy or biopsy for 245 chimpanzees (Pan troglodytes) over a 35-year period. A review of the pathology database was performed for all diagnoses on chimpanzees from 1980 to 2014. All morphologic diagnoses, associated system, organ, etiology, and demographic information were reviewed and analyzed. Cardiomyopathy was the most frequent lesion observed followed by hemosiderosis, hyperplasia, nematodiasis, edema, and hemorrhage. The most frequently affected systems were the gastrointestinal, cardiovascular, urogenital, respiratory, and lymphatic/hematopoietic systems. The most common etiology was undetermined, followed by degenerative, physiologic, neoplastic, parasitic, and bacterial. Perinatal and infant animals were mostly affected by physiologic etiologies and chimpanzee-induced trauma. Bacterial and physiologic etiologies were more common in juvenile animals. Degenerative and physiologic (and neoplastic in geriatric animals) etiologies predominated in adult, middle aged, and geriatric chimpanzees.

Original languageEnglish (US)
Pages (from-to)271-290
Number of pages20
JournalJournal of medical primatology
Volume46
Issue number5
DOIs
StatePublished - Oct 2017
Externally publishedYes

Keywords

  • aging
  • cardiomyopathy
  • chimpanzee
  • geriatric
  • lesions
  • pathology
  • primates

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Fingerprint

Dive into the research topics of 'Natural pathology of the captive chimpanzee (Pan troglodytes): A 35-year review'. Together they form a unique fingerprint.

Cite this