Natural pathology of the Baboon (Papio spp.)

Yugendar R. Bommineni, Edward J. Dick, Adinarayana R. Malapati, Michael A. Owston, Gene B. Hubbard

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Background Baboons are useful animal models for biomedical research, but the natural pathology of the baboon is not as well defined as other non-human primates. Methods A computer search for all morphologic diagnoses from baboon necropsies at the Southwest National Primate Research Center was performed and included all the natural deaths and animals euthanized for natural causes. Results A total of 10,883 macroscopic or microscopic morphologic diagnoses in 4297 baboons were documented and are presented by total incidence, relative incidence by sex and age-group, and mean age of occurrence. The most common diagnoses in descending order of occurrence were hemorrhage, stillborn, amyloidosis, colitis, spondylosis, and pneumonia. The systems with the most diagnoses were the digestive, urogenital, musculoskeletal, and respiratory. Conclusion This extensive evaluation of the natural pathology of the baboon should be an invaluable biomedical research resource.

Original languageEnglish (US)
Pages (from-to)142-155
Number of pages14
JournalJournal of medical primatology
Volume40
Issue number2
DOIs
StatePublished - Apr 2011

Keywords

  • Diseases
  • Monkey
  • Non-human primates
  • Pathology
  • Spontaneous
  • Survey

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

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