TY - JOUR
T1 - National trends in hospitalization and mortality rates for patients with HIV, HCV, or HIV/HCV coinfection from 1996-2010 in the United States
T2 - A cross-sectional study
AU - Oramasionwu, Christine U.
AU - Toliver, Joshua C.
AU - Johnson, Terence L.
AU - Moore, Heather N.
AU - Frei, Christopher R.
N1 - Funding Information:
This study was funded by The University of North Carolina Junior Faculty Development Award, awarded to Dr. Oramasionwu. Dr. Oramasionwu was also supported in part by the NIH Loan Repayment Program (LRP) through the National Institute on Minority Health and Health Disparities (Grant number: L60 MD003770). Additionally, parts of this study were presented at the 2012 and 2013 annual IDWeek meetings in San Diego, CA (October 17–21, 2012) and San Francisco, CA (October 2–6, 2013).
Funding Information:
This study was funded by The University of North Carolina Junior Faculty Development Award, awarded to Dr. Oramasionwu. Dr. Oramasionwu was also supported in part by the NIH Loan Repayment Program (LRP) through the National Institute on Minority Health and Health Disparities (Grant number: L60 MD003770). Additionally, parts of this study were presented at the 2012 and 2013 annual IDWeek meetings in San Diego, CA (October 17-21, 2012) and San Francisco, CA (October 2-6, 2013).
Publisher Copyright:
© 2014 Oramasionwu et al.
PY - 2014/10/10
Y1 - 2014/10/10
N2 - Background: The comparative impact of chronic viral monoinfection versus coinfection on inpatient outcomes and health care utilization is relatively unknown. This study examined trends, inpatient utilization, and hospital outcomes for patients with HIV, HCV, or HIV/HCV coinfection. Methods: Data were from the 1996-2010 National Hospital Discharge Surveys. Hospitalizations with primary ICD-9-CM codes for HIV or HCV were included for HIV and HCV monoinfection, respectfully. Coinfection included both HIV and HCV codes. Demographic characteristics, select comorbidities, procedural interventions, average hospital length of stay (LOS), and discharge status were compared by infection status (HIV, HCV, HIV/HCV). Annual disease estimates and survey weights were used to generate hospitalization rates. Results: ~6.6 million hospitalizations occurred in patients with HIV (39%), HCV (56%), or HIV/HCV (5%). The hospitalization rate (hospitalizations per 100 persons with infection) decreased in the HIV group (29.8 in 1996; 5.3 in 2010), decreased in the HIV/HCV group (2.0 in 1996; 1.5 in 2010), yet increased in the HCV group (0.2 in 1996; 0.9 in 2010). Median LOS from 1996 to 2010 (days, interquartile range) decreased in all groups: HIV, 6 (3-10) to 4 (3-8); HCV, 5 (3-9) to 4 (2-6); HIV/HCV, 6 (4-11) to 4 (2-7). Age-adjusted mortality rates decreased for all three groups. The rate of decline was least pronounced for those with HCV monoinfection. Conclusion: Hospitalizations have declined more rapidly for patients with HIV infection (including HIV/HCV coinfection) than for patients with HCV infection. This growing disparity between HIV and HCV underscores the need to allocate more resources to HCV care in hopes that similar large-scale improvements can also be accomplished for patients with HCV.
AB - Background: The comparative impact of chronic viral monoinfection versus coinfection on inpatient outcomes and health care utilization is relatively unknown. This study examined trends, inpatient utilization, and hospital outcomes for patients with HIV, HCV, or HIV/HCV coinfection. Methods: Data were from the 1996-2010 National Hospital Discharge Surveys. Hospitalizations with primary ICD-9-CM codes for HIV or HCV were included for HIV and HCV monoinfection, respectfully. Coinfection included both HIV and HCV codes. Demographic characteristics, select comorbidities, procedural interventions, average hospital length of stay (LOS), and discharge status were compared by infection status (HIV, HCV, HIV/HCV). Annual disease estimates and survey weights were used to generate hospitalization rates. Results: ~6.6 million hospitalizations occurred in patients with HIV (39%), HCV (56%), or HIV/HCV (5%). The hospitalization rate (hospitalizations per 100 persons with infection) decreased in the HIV group (29.8 in 1996; 5.3 in 2010), decreased in the HIV/HCV group (2.0 in 1996; 1.5 in 2010), yet increased in the HCV group (0.2 in 1996; 0.9 in 2010). Median LOS from 1996 to 2010 (days, interquartile range) decreased in all groups: HIV, 6 (3-10) to 4 (3-8); HCV, 5 (3-9) to 4 (2-6); HIV/HCV, 6 (4-11) to 4 (2-7). Age-adjusted mortality rates decreased for all three groups. The rate of decline was least pronounced for those with HCV monoinfection. Conclusion: Hospitalizations have declined more rapidly for patients with HIV infection (including HIV/HCV coinfection) than for patients with HCV infection. This growing disparity between HIV and HCV underscores the need to allocate more resources to HCV care in hopes that similar large-scale improvements can also be accomplished for patients with HCV.
KW - Coinfection
KW - HCV
KW - HIV
KW - Health care utilization
KW - Hospitalization
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U2 - 10.1186/1471-2334-14-536
DO - 10.1186/1471-2334-14-536
M3 - Article
C2 - 25300638
AN - SCOPUS:84964315566
VL - 14
JO - BMC Infectious Diseases
JF - BMC Infectious Diseases
SN - 1471-2334
IS - 1
M1 - 536
ER -