N-acetyltransferase activity and indole contents of the male syrian hamster harderian gland

Changes during the light:dark cycle

Armando Menendez-Pelaez, Russel J Reiter, Aldo Gonzalez-Brito, Kimberly A. Howes

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The activities of N-acetyltransferase (NAT) and hydroxyindole-O-methyltransferase (HIOMT) and the indole contents of the Harderian glands of male Syrian hamsters were studied throughout a 24-h period. NAT activity exhibited a sharp rise 1 h after lights on, decreasing to basal levels 1 h later. Neither a HIOMT activity nor a melatonin concentration rhythm was detected throughout the 24 h. The 5-hydroxytryptamine (serotonin) concentration was highest during the dark phase reaching a peak at 0300 h; with light onset serotonin levels exhibited a rapid short-term drop. The 5-hydroxytryptophol concentration was highest during the mid- to late photophase; the lowest values to this constituent were measured late in the dark phase and at 1 h after lights on. The 5-hydroxyindole acetic acid concentration of the Harderian glands was rather stable throughout the 24-h period but levels did show a short-lived drop 1 h after light onset. Only a few animals contained detectable amounts of N-acetyl-5-hydroxytryptamine (N-acetylserotonin) in their Harderian glands. In agreement with previous work on the Harderian glands of female Syrian hamsters, the present results in males suggest that light onset is associated with marked changes in Harderian indoleamine metabolism.

Original languageEnglish (US)
Pages (from-to)20-25
Number of pages6
JournalArchives of Biochemistry and Biophysics
Volume268
Issue number1
DOIs
StatePublished - 1989

Fingerprint

Harderian Gland
Acetyltransferases
Mesocricetus
Photoperiod
Light
Acetylserotonin O-Methyltransferase
Serotonin
Hydroxytryptophol
Melatonin
Metabolism
Acetic Acid
Animals
indole

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

N-acetyltransferase activity and indole contents of the male syrian hamster harderian gland : Changes during the light:dark cycle. / Menendez-Pelaez, Armando; Reiter, Russel J; Gonzalez-Brito, Aldo; Howes, Kimberly A.

In: Archives of Biochemistry and Biophysics, Vol. 268, No. 1, 1989, p. 20-25.

Research output: Contribution to journalArticle

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