Myxomatous neoplasms in the perineal region of baboons

Shannon M. Wallace, Kathleen A. Szabo, Natalia E. Schlabritz-Loutsevitch, Edward J. Dick, Terrell W. Blanchard, Gene B. Hubbard

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Background: In baboons, Papio sp. neoplasms tend to affect the hematopoietic system most commonly, with rare documentation of myxomatous neoplasms. In contrast, women can develop myxomatous masses within deep peripelvic tissues with some frequency during their reproductive years. Methods: We have identified and examined, retrospectively, myxomatous perineal masses in twelve female baboons within one research facility and compared their histopathologic, immunohistochemical and electron microscopic features to their human variants. Results: Our results indicate that these myxomatous neoplasms, in humans and non-human primates, share common features. Conclusion: Further research, particularly molecular genetic analysis, may be needed to identify the baboon as a true animal model for myxomatous perineal neoplasms.

Original languageEnglish (US)
Pages (from-to)261-270
Number of pages10
JournalJournal of medical primatology
Volume37
Issue number6
DOIs
StatePublished - 2008
Externally publishedYes

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

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    Wallace, S. M., Szabo, K. A., Schlabritz-Loutsevitch, N. E., Dick, E. J., Blanchard, T. W., & Hubbard, G. B. (2008). Myxomatous neoplasms in the perineal region of baboons. Journal of medical primatology, 37(6), 261-270. https://doi.org/10.1111/j.1600-0684.2008.00293.x