MyoD1 protein expression in alveolar soft part sarcoma as confirmatory evidence of its skeletal muscle nature

J. Rosai; P. Dias; D. M. Parham; D. N. Shapiro; P. Houghton

doi:10.1097/00000478-199110000-00008

MyoD1 protein expression in alveolar soft part sarcoma as confirmatory evidence of its skeletal muscle nature

J. Rosai, P. Dias, D. M. Parham, D. N. Shapiro, P. Houghton

Research output: Contribution to journal › Article › peer-review

98 Scopus citations

Abstract

A typical case of alveolar soft part sarcoma was found to express in a strong and widespread fashion the marker MyoD1 protein. This nuclear phosphoprotein is the product of a regulatory gene that controls the commitment of a cell to myogenic lineage; it therefore provides strong and perhaps definitive evidence in support of the skeletal muscle nature of this enigmatic neoplasm.

Original language	English (US)
Pages (from-to)	974-981
Number of pages	8
Journal	American Journal of Surgical Pathology
Volume	15
Issue number	10
DOIs	https://doi.org/10.1097/00000478-199110000-00008
State	Published - Jan 1 1991
Externally published	Yes

Keywords

Alveolar soft part sarcoma
MyoD1
MyoD1 protein
Skeletal muscle
Soft tissue tumors

ASJC Scopus subject areas

Anatomy
Surgery
Pathology and Forensic Medicine

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10.1097/00000478-199110000-00008

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abstract = "A typical case of alveolar soft part sarcoma was found to express in a strong and widespread fashion the marker MyoD1 protein. This nuclear phosphoprotein is the product of a regulatory gene that controls the commitment of a cell to myogenic lineage; it therefore provides strong and perhaps definitive evidence in support of the skeletal muscle nature of this enigmatic neoplasm.",

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AU - Dias, P.

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AU - Shapiro, D. N.

AU - Houghton, P.

PY - 1991/1/1

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N2 - A typical case of alveolar soft part sarcoma was found to express in a strong and widespread fashion the marker MyoD1 protein. This nuclear phosphoprotein is the product of a regulatory gene that controls the commitment of a cell to myogenic lineage; it therefore provides strong and perhaps definitive evidence in support of the skeletal muscle nature of this enigmatic neoplasm.

AB - A typical case of alveolar soft part sarcoma was found to express in a strong and widespread fashion the marker MyoD1 protein. This nuclear phosphoprotein is the product of a regulatory gene that controls the commitment of a cell to myogenic lineage; it therefore provides strong and perhaps definitive evidence in support of the skeletal muscle nature of this enigmatic neoplasm.

KW - Alveolar soft part sarcoma

KW - MyoD1

KW - MyoD1 protein

KW - Skeletal muscle

KW - Soft tissue tumors

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MyoD1 protein expression in alveolar soft part sarcoma as confirmatory evidence of its skeletal muscle nature

Abstract

Keywords

ASJC Scopus subject areas

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