Myocardial ischemia and stunning induced by topical intranasal phenylephrine pledgets

Richard B. Hecker, Jerry D. Champ, Janet V. Hays, Bernard J. Rubal

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


This case study describes myocardial ischemia and stunning after the topical application of phenylephrine-soaked pledgers (0.25%) in a 63-year- old female undergoing elective endoscopic sinus surgery. The patient had no previous history of cardiovascular disease or illicit drug use. Transient myocardial ischemia was associated with acute hypertension, chest pain, and S-T segment changes 4 minutes after pledget placement. Angiography revealed normal coronary blood flow and severe left ventricular systolic and diastolic dysfunction. Follow-up echo-cardiography demonstrated improved left ventricular function within 1 week and total resolution of dysfunction by 4 weeks after ischemia.

Original languageEnglish (US)
Pages (from-to)832-835
Number of pages4
JournalMilitary medicine
Issue number12
StatePublished - Dec 1997

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health


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