Myocardial ischemia and stunning induced by topical intranasal phenylephrine pledgets

Richard B. Hecker; Jerry D. Champ; Janet V. Hays; Bernard J. Rubal

doi:10.1093/milmed/162.12.832

Myocardial ischemia and stunning induced by topical intranasal phenylephrine pledgets

Richard B. Hecker, Jerry D. Champ, Janet V. Hays, Bernard J. Rubal

Division of Cardiology

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

This case study describes myocardial ischemia and stunning after the topical application of phenylephrine-soaked pledgers (0.25%) in a 63-year- old female undergoing elective endoscopic sinus surgery. The patient had no previous history of cardiovascular disease or illicit drug use. Transient myocardial ischemia was associated with acute hypertension, chest pain, and S-T segment changes 4 minutes after pledget placement. Angiography revealed normal coronary blood flow and severe left ventricular systolic and diastolic dysfunction. Follow-up echo-cardiography demonstrated improved left ventricular function within 1 week and total resolution of dysfunction by 4 weeks after ischemia.

Original language	English (US)
Pages (from-to)	832-835
Number of pages	4
Journal	Military medicine
Volume	162
Issue number	12
DOIs	https://doi.org/10.1093/milmed/162.12.832
State	Published - Dec 1997

ASJC Scopus subject areas

Public Health, Environmental and Occupational Health

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10.1093/milmed/162.12.832

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abstract = "This case study describes myocardial ischemia and stunning after the topical application of phenylephrine-soaked pledgers (0.25%) in a 63-year- old female undergoing elective endoscopic sinus surgery. The patient had no previous history of cardiovascular disease or illicit drug use. Transient myocardial ischemia was associated with acute hypertension, chest pain, and S-T segment changes 4 minutes after pledget placement. Angiography revealed normal coronary blood flow and severe left ventricular systolic and diastolic dysfunction. Follow-up echo-cardiography demonstrated improved left ventricular function within 1 week and total resolution of dysfunction by 4 weeks after ischemia.",

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AB - This case study describes myocardial ischemia and stunning after the topical application of phenylephrine-soaked pledgers (0.25%) in a 63-year- old female undergoing elective endoscopic sinus surgery. The patient had no previous history of cardiovascular disease or illicit drug use. Transient myocardial ischemia was associated with acute hypertension, chest pain, and S-T segment changes 4 minutes after pledget placement. Angiography revealed normal coronary blood flow and severe left ventricular systolic and diastolic dysfunction. Follow-up echo-cardiography demonstrated improved left ventricular function within 1 week and total resolution of dysfunction by 4 weeks after ischemia.

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Myocardial ischemia and stunning induced by topical intranasal phenylephrine pledgets

Abstract

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