Myocardial Ischemia

L. David Hillis, Eugene Braunwald

Research output: Contribution to journalReview articlepeer-review

65 Scopus citations


Biochemical Technics It has been known for over 20 years that irreversibly injured myocardial cells release enzymes. In the hours after an acute myocardial infarction, the plasma concentrations of these enzymes gradually rise, reach a peak and then fall progressively. The laboratory measurement of serum enzymes is a standard practice in the diagnosis of acute myocardial infarction. Lactic dehydrogenase (LDH) is elevated in the several days after an acute myocardial infarction; this enzyme can be separated into five distinct components or isoenzymes, according to their speed of migration in an electrophoretic field. The myocardium contains predominantly LDH5, although.

Original languageEnglish (US)
Pages (from-to)1034-1041
Number of pages8
JournalNew England Journal of Medicine
Issue number18
StatePublished - May 5 1977
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Myocardial Ischemia'. Together they form a unique fingerprint.

Cite this