Myeloproliferative disorders and the hyperviscosity syndrome

Bruce D. Adams; Russell Baker; J. Abraham Lopez; Susan Spencer

doi:10.1016/j.hoc.2010.03.004

Myeloproliferative disorders and the hyperviscosity syndrome

Bruce D. Adams, Russell Baker, J. Abraham Lopez, Susan Spencer

Emergency Medicine

Research output: Contribution to journal › Review article › peer-review

18 Scopus citations

Abstract

Myeloproliferative disorders and the serum hyperviscosity syndrome can rapidly manifest with emergent presentations. Hyperviscosity occurs from pathologic elevations of either the cellular or acellular (protein) fractions of the circulating blood. Classic hyperviscosity syndrome presents with the triad of bleeding diathesis, visual disturbances, and focal neurologic signs. Emergency medicine providers should be aware of these conditions and be prepared to rapidly initiate supportive and early definitive management, including plasma exchange and apharesis. Early consultation with a hematologist is essential to managing these complex patients.

Original language	English (US)
Pages (from-to)	585-602
Number of pages	18
Journal	Hematology/Oncology Clinics of North America
Volume	24
Issue number	3
DOIs	https://doi.org/10.1016/j.hoc.2010.03.004
State	Published - Jun 1 2010

Keywords

Essential thrombocytosis
Hyperleukocytosis
Hyperviscosity syndrome
Leukostasis
Polycythemia vera
Waldenstrom macroglobulinemia

ASJC Scopus subject areas

Hematology
Oncology

Access to Document

10.1016/j.hoc.2010.03.004

Fingerprint Dive into the research topics of 'Myeloproliferative disorders and the hyperviscosity syndrome'. Together they form a unique fingerprint.

Cite this

@article{e3a069a4b53a4bd78e80b2f022db1026,

title = "Myeloproliferative disorders and the hyperviscosity syndrome",

abstract = "Myeloproliferative disorders and the serum hyperviscosity syndrome can rapidly manifest with emergent presentations. Hyperviscosity occurs from pathologic elevations of either the cellular or acellular (protein) fractions of the circulating blood. Classic hyperviscosity syndrome presents with the triad of bleeding diathesis, visual disturbances, and focal neurologic signs. Emergency medicine providers should be aware of these conditions and be prepared to rapidly initiate supportive and early definitive management, including plasma exchange and apharesis. Early consultation with a hematologist is essential to managing these complex patients.",

keywords = "Essential thrombocytosis, Hyperleukocytosis, Hyperviscosity syndrome, Leukostasis, Polycythemia vera, Waldenstrom macroglobulinemia",

author = "Adams, {Bruce D.} and Russell Baker and Lopez, {J. Abraham} and Susan Spencer",

year = "2010",

month = jun,

day = "1",

doi = "10.1016/j.hoc.2010.03.004",

language = "English (US)",

volume = "24",

pages = "585--602",

journal = "Hematology/Oncology Clinics of North America",

issn = "0889-8588",

publisher = "W.B. Saunders Ltd",

number = "3",

}

TY - JOUR

T1 - Myeloproliferative disorders and the hyperviscosity syndrome

AU - Adams, Bruce D.

AU - Baker, Russell

AU - Lopez, J. Abraham

AU - Spencer, Susan

PY - 2010/6/1

Y1 - 2010/6/1

N2 - Myeloproliferative disorders and the serum hyperviscosity syndrome can rapidly manifest with emergent presentations. Hyperviscosity occurs from pathologic elevations of either the cellular or acellular (protein) fractions of the circulating blood. Classic hyperviscosity syndrome presents with the triad of bleeding diathesis, visual disturbances, and focal neurologic signs. Emergency medicine providers should be aware of these conditions and be prepared to rapidly initiate supportive and early definitive management, including plasma exchange and apharesis. Early consultation with a hematologist is essential to managing these complex patients.

AB - Myeloproliferative disorders and the serum hyperviscosity syndrome can rapidly manifest with emergent presentations. Hyperviscosity occurs from pathologic elevations of either the cellular or acellular (protein) fractions of the circulating blood. Classic hyperviscosity syndrome presents with the triad of bleeding diathesis, visual disturbances, and focal neurologic signs. Emergency medicine providers should be aware of these conditions and be prepared to rapidly initiate supportive and early definitive management, including plasma exchange and apharesis. Early consultation with a hematologist is essential to managing these complex patients.

KW - Essential thrombocytosis

KW - Hyperleukocytosis

KW - Hyperviscosity syndrome

KW - Leukostasis

KW - Polycythemia vera

KW - Waldenstrom macroglobulinemia

UR - http://www.scopus.com/inward/record.url?scp=77952949493&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77952949493&partnerID=8YFLogxK

U2 - 10.1016/j.hoc.2010.03.004

DO - 10.1016/j.hoc.2010.03.004

M3 - Review article

C2 - 20488356

AN - SCOPUS:77952949493

VL - 24

SP - 585

EP - 602

JO - Hematology/Oncology Clinics of North America

JF - Hematology/Oncology Clinics of North America

SN - 0889-8588

IS - 3

ER -