Mycobacterium avium infections in man

George A. Falk, Susan J. Hadley, Francis E Sharkey, Mildred Liss, Carl Muschenheim

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

A disseminated infection with Mycobacterium avium, serotype 1, is described in a 63 year old woman with reticulum cell sarcoma. The organism was demonstrated in vivo in lymph nodes, bone marrow, urine and sputum, and at autopsy within an intraocular abscess. Previous reports of human infections with Myco. avium describe cases of chronic, cavitary pulmonary disease, frequently occurring in patients with pneumoconiosis, cervical lymphadenopathy in children, and disseminated infection. Infected birds and mammals, and soil rich in bird droppings appear to constitute natural reservoirs of infection. However, extensive exposure to birds or the carcasses of slaughtered animals has been documented in only a minority of cases. Myco. avium can be reliably identified only by serotyping or by inoculation into chickens, rabbits and guinea pigs. Skin tests with avian purified protein derivative together with standard purified protein derivatives and antigens prepared from other mycobacteria may be helpful in diagnosis prior to isolation and identification of the organism. Although localized infections have apparently been cured by surgical excision, more extensive infections have been reported to be progressive or fatal and have responded poorly to chemotherapy.

Original languageEnglish (US)
Pages (from-to)801-810
Number of pages10
JournalThe American journal of medicine
Volume54
Issue number6
DOIs
StatePublished - 1973
Externally publishedYes

Fingerprint

Mycobacterium avium
Mycobacterium Infections
Infection
Birds
Avian Proteins
Pneumoconiosis
Serotyping
Mycobacterium
Skin Tests
Sputum
Non-Hodgkin's Lymphoma
Abscess
Lung Diseases
Mammals
Autopsy
Chickens
Guinea Pigs
Soil
Lymph Nodes
Bone Marrow

ASJC Scopus subject areas

  • Nursing(all)

Cite this

Falk, G. A., Hadley, S. J., Sharkey, F. E., Liss, M., & Muschenheim, C. (1973). Mycobacterium avium infections in man. The American journal of medicine, 54(6), 801-810. https://doi.org/10.1016/0002-9343(73)90069-7

Mycobacterium avium infections in man. / Falk, George A.; Hadley, Susan J.; Sharkey, Francis E; Liss, Mildred; Muschenheim, Carl.

In: The American journal of medicine, Vol. 54, No. 6, 1973, p. 801-810.

Research output: Contribution to journalArticle

Falk, GA, Hadley, SJ, Sharkey, FE, Liss, M & Muschenheim, C 1973, 'Mycobacterium avium infections in man', The American journal of medicine, vol. 54, no. 6, pp. 801-810. https://doi.org/10.1016/0002-9343(73)90069-7
Falk GA, Hadley SJ, Sharkey FE, Liss M, Muschenheim C. Mycobacterium avium infections in man. The American journal of medicine. 1973;54(6):801-810. https://doi.org/10.1016/0002-9343(73)90069-7
Falk, George A. ; Hadley, Susan J. ; Sharkey, Francis E ; Liss, Mildred ; Muschenheim, Carl. / Mycobacterium avium infections in man. In: The American journal of medicine. 1973 ; Vol. 54, No. 6. pp. 801-810.
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