Abstract
MICs of fluconazole and amphotericin B were determined independently for 100 coded yeast isolates by each of six laboratories to determine reproducibility of results by using a colorimetric oxidation-reduction-based broth microdilution test. In addition, each site tested five quality control isolates on at least four different occasions during the study. Results agreed within a three-dilution range (mode ± 1 log2 dilution) for 96.2% of fluconazole tests and 92.7% of amphotericin B tests. Agreement among tests with the quality control isolates was 99.4% with fluconazole and 98.65 with amphotericin B. These results indicate that the colorimetric microdilution method is reproducible among laboratories.
Original language | English (US) |
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Pages (from-to) | 1625-1628 |
Number of pages | 4 |
Journal | Journal of clinical microbiology |
Volume | 32 |
Issue number | 7 |
DOIs | |
State | Published - 1994 |
ASJC Scopus subject areas
- Microbiology (medical)