Multiple cutaneous plexiform schwannomas as initial presentation of neurofibromatosis 2 in a 9-year-old

Tien V. Nguyen, Mark R. Matthews, Fernando F. Barrera, John C. Browning

Research output: Contribution to journalShort survey

6 Scopus citations

Abstract

Neurofibromatosis 2 (NF2) is an autosomal-dominant disease caused by genetic mutations of the NF2 gene on chromosome 22. Patients are often diagnosed according to the presence of bilateral vestibular schwannomas and other tumors in the brain and spinal cord. In children, NF2 can present early with ocular findings and cutaneous tumors. We report here a 9-year-old girl who presented with multiple pigmented, slightly tender plaques on her scalp, face, and back that were revealed by histopathology to be plexiform schwannomas. We suspected NF2 and sent the patient's blood for genetic testing, which confirmed our diagnosis.

Original languageEnglish (US)
Pages (from-to)536-538
Number of pages3
JournalPediatric dermatology
Volume29
Issue number4
DOIs
StatePublished - Jul 1 2012

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Dermatology

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