Multidrug-resistant pathogens in patients with pneumonia coming from the community

Oriol Sibila, Ana Rodrigo-Troyano, Yuichiro Shindo, Stefano Aliberti, Marcos I. Restrepo

Research output: Contribution to journalReview articlepeer-review

21 Scopus citations


Purpose of review Identification of patients with multidrug-resistant (MDR) pathogens at initial diagnosis is essential for the appropriate selection of empiric treatment of patients with pneumonia coming from the community. The term Healthcare-Associated Pneumonia (HCAP) is controversial for this purpose. Our goal is to summarize and interpret the data addressing the association of MDR pathogens and community-onset pneumonia. Recent findings Most recent clinical studies conclude that HCAP risk factor does not accurately identify resistant pathogens. Several risk factors related to MDR pathogens, including new ones that were not included in the original HCAP definition, have been described and different risk scores have been proposed. The present review focuses on the most recent literature assessing the importance of different risk factors for MDR pathogens in patients with pneumonia coming from the community. These included generally MDR risk factors, specific risk factors related to methicillin-resistant Staphylococcus aureus or Pseudomonas aeruginosa and clinical scoring systems develop to assess the MDR risk factors and its application in clinical practice. Summary Different MDR risk factors and prediction scores have been recently developed. However, further research is needed in order to help clinicians in distinguishing between different MDR pathogens causing pneumonia.

Original languageEnglish (US)
Pages (from-to)219-226
Number of pages8
JournalCurrent Opinion in Pulmonary Medicine
Issue number3
StatePublished - May 1 2016


  • Pseudomonas
  • community-acquired pneumonia
  • healthcare-associated pneumonia
  • methicillin-resistant Staphylococcus aureus
  • risk scores

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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