Multi-institutional experience with the in-office potassium Titanyl phosphate laser for laryngeal lesions

Mike Sheu, Shaum Sridharan, Maggie Kuhn, Sean Wang, Benjamin Paul, Naren Venkatesan, Colin W. Fuller, C. Blake Simpson, Michael Johns, Ryan C. Branski, Milan R. Amin

Research output: Contribution to journalArticle

26 Scopus citations

Abstract

Objective/Hypothesis: To determine the efficacy of the potassium titanyl phosphate (KTP) laser in lesion reduction, as well as preservation of mucosal wave and glottic closure in a cohort of patients with benign laryngeal pathology across multiple institutions. Study Design: Multi-institutional and retrospective. Methods: One hundred two patients who underwent in-office KTP procedures at multiple academic laryngology practices with at least a single follow-up visit were included. Image analysis was used to quantify vocal fold lesion size before and after treatment. A subset of images was analyzed by expert reviewers to determine the impact of this treatment on glottic closure and mucosal wave. Results: Statistically, when considering all lesions, KTP induced a significant reduction in lesion size. Post hoc analyses revealed some lesion specificity; all lesions decreased in size, with the exception of vocal fold scar. Mucosal wave and glottic closure were improved or unchanged in more than 90% of the patients examined. The inter- and intrarater reliabilities of the lesion quantification method were excellent. Conclusions: With great care and insight, the KTP laser appears to be a valuable tool for the treatment of various benign laryngeal lesions. Furthermore, KTP laser therapy appears to preserve or improve mucosal wave and glottic closure. The lesion measurement protocol previously described by our group appears to be reliable.

Original languageEnglish (US)
Pages (from-to)806-810
Number of pages5
JournalJournal of Voice
Volume26
Issue number6
DOIs
StatePublished - Nov 1 2012

Keywords

  • Glottic closure
  • KTP
  • Mucosal wave
  • Potassium titanyl phosphate
  • Vocal fold
  • Voice

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Speech and Hearing
  • LPN and LVN

Fingerprint Dive into the research topics of 'Multi-institutional experience with the in-office potassium Titanyl phosphate laser for laryngeal lesions'. Together they form a unique fingerprint.

  • Cite this

    Sheu, M., Sridharan, S., Kuhn, M., Wang, S., Paul, B., Venkatesan, N., Fuller, C. W., Simpson, C. B., Johns, M., Branski, R. C., & Amin, M. R. (2012). Multi-institutional experience with the in-office potassium Titanyl phosphate laser for laryngeal lesions. Journal of Voice, 26(6), 806-810. https://doi.org/10.1016/j.jvoice.2012.04.003