MU-Tomo: Independent dose validation software for helical tomotherapy

Nikos Papanikolaou, Weihong He, A. Vazquez Q. Luis, Alonso Gutierrez, Sotirios Stathakis, Hassaan Alkhatib, Chengyu Shi

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


A software program, MU-Tomo, has been developed to perform an independent point dose calculation and compare it to the dose calculated from the TomoTherapy (TomoTherapy, Inc., Madison, WI) treatment planning system (TPS). Input parameters required for this software include: archived tomotherapy patient files, QA plan image coordinates, tomotherapy-calculated point dose and machine-specifi c dosimetric parameters such as the off-axis ratios (OARx and OARy), tissue phantom ratios (TPR) and output functions (Scp). The software was validated on four phantom models and fifty tomotherapy patient plans representing various anatomical sites. Our results indicate that MU-Tomo can perform in a few seconds an independent dose calculation accurately and provide a secondary check for a point dose validation of helical tomotherapy plans.

Original languageEnglish (US)
Pages (from-to)145-152
Number of pages8
JournalJournal of Cancer Science and Therapy
Issue number5
StatePublished - 2010


  • Dose verification
  • Independent dose calculation
  • Second check
  • TomoTherapy

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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