MRI study of corpus callosum in children and adolescents with bipolar disorder

A. Sibel Yasar; E. Serap Monkul; Roberto B. Sassi; David Axelson; Paolo Brambilla; Mark A. Nicoletti; John P. Hatch; Matcheri Keshavan; Neal Ryan; Boris Birmaher; Jair C. Soares

doi:10.1016/j.pscychresns.2005.09.004

MRI study of corpus callosum in children and adolescents with bipolar disorder

A. Sibel Yasar, E. Serap Monkul, Roberto B. Sassi, David Axelson, Paolo Brambilla, Mark A. Nicoletti, John P. Hatch, Matcheri Keshavan, Neal Ryan, Boris Birmaher, Jair C. Soares

Psychiatry

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Abstract

This structural magnetic resonance imaging study examined the length, areas, and circularity of the corpus callosum (CC) in 16 children and adolescents with bipolar disorder and 21 healthy controls. Bipolar disorder patients had lower circularity of the CC splenium compared with healthy controls. No significant differences in CC length or area were observed, suggesting that reported CC abnormalities appear late in the course of bipolar disorder.

Original language	English (US)
Pages (from-to)	83-85
Number of pages	3
Journal	Psychiatry Research - Neuroimaging
Volume	146
Issue number	1
DOIs	https://doi.org/10.1016/j.pscychresns.2005.09.004
State	Published - Jan 30 2006

Keywords

Mood disorders
Neuroimaging
White matter

ASJC Scopus subject areas

Neuroscience (miscellaneous)
Radiology Nuclear Medicine and imaging
Psychiatry and Mental health

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10.1016/j.pscychresns.2005.09.004

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MRI study of corpus callosum in children and adolescents with bipolar disorder. / Yasar, A. Sibel; Monkul, E. Serap; Sassi, Roberto B.; Axelson, David; Brambilla, Paolo; Nicoletti, Mark A.; Hatch, John P.; Keshavan, Matcheri; Ryan, Neal; Birmaher, Boris; Soares, Jair C.

In: Psychiatry Research - Neuroimaging, Vol. 146, No. 1, 30.01.2006, p. 83-85.

Research output: Contribution to journal › Article › peer-review

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abstract = "This structural magnetic resonance imaging study examined the length, areas, and circularity of the corpus callosum (CC) in 16 children and adolescents with bipolar disorder and 21 healthy controls. Bipolar disorder patients had lower circularity of the CC splenium compared with healthy controls. No significant differences in CC length or area were observed, suggesting that reported CC abnormalities appear late in the course of bipolar disorder.",

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note = "Funding Information: This work was partly supported by grants MH 01736, MH 55123, MH 30915, and MH 59929 from the National Institute of Mental Health, RR020571 from the National Center for Research Resources, NARSAD, the Krus Endowed Chair in Psychiatry (The University of Texas Health Science Center at San Antonio) and the CAPES Foundation (Brazil).",

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AU - Yasar, A. Sibel

AU - Monkul, E. Serap

AU - Sassi, Roberto B.

AU - Axelson, David

AU - Brambilla, Paolo

AU - Nicoletti, Mark A.

AU - Hatch, John P.

AU - Keshavan, Matcheri

AU - Ryan, Neal

AU - Birmaher, Boris

AU - Soares, Jair C.

N1 - Funding Information: This work was partly supported by grants MH 01736, MH 55123, MH 30915, and MH 59929 from the National Institute of Mental Health, RR020571 from the National Center for Research Resources, NARSAD, the Krus Endowed Chair in Psychiatry (The University of Texas Health Science Center at San Antonio) and the CAPES Foundation (Brazil).

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N2 - This structural magnetic resonance imaging study examined the length, areas, and circularity of the corpus callosum (CC) in 16 children and adolescents with bipolar disorder and 21 healthy controls. Bipolar disorder patients had lower circularity of the CC splenium compared with healthy controls. No significant differences in CC length or area were observed, suggesting that reported CC abnormalities appear late in the course of bipolar disorder.

AB - This structural magnetic resonance imaging study examined the length, areas, and circularity of the corpus callosum (CC) in 16 children and adolescents with bipolar disorder and 21 healthy controls. Bipolar disorder patients had lower circularity of the CC splenium compared with healthy controls. No significant differences in CC length or area were observed, suggesting that reported CC abnormalities appear late in the course of bipolar disorder.

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KW - Neuroimaging

KW - White matter

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MRI study of corpus callosum in children and adolescents with bipolar disorder

Abstract

Keywords

ASJC Scopus subject areas

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