Mortalities associated with use of a commercial suspension of polyvinyl alcohol

I. Repa, G. P. Moradian, L. P. Dehner, S. M. Tadavarthy, D. W. Hunter, W. R. Castaneda-Zuniga, G. B. Wright, H. Katkov, P. Johnson, B. Chrenka, K. Amplatz

Research output: Contribution to journalArticlepeer-review

41 Scopus citations


Two cases of symptomatic neonatal hepatic arteriovenous malformation (AVM) are presented. Both were treated with percutaneous transcatheter embolization and a commercially available polyvinyl alcohol suspension. Both infants died soon after AVM embolization. The results of laboratory examination of particle-size homogeneity of this commercial suspension demonstrate marked inhomogeneity of particle size very probably contributed to the death of these patients. A protocol has been developed to help determine appropriate particle size in individual cases; this may help prevent such catastrophic results during transcatheter embolization.

Original languageEnglish (US)
Pages (from-to)395-399
Number of pages5
Issue number2
StatePublished - 1989

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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