Morphometric analysis of pancreatic acinar cells from orally fed and intravenously fed rats

William A. Pavlat, Waid Rogers, Ivan L. Cameron

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

This report concerns the effects of 1 week of total parenteral (iv) nutrition on the pancreatic acinar cells of the rat. The results indicate that total iv feeding causes a 50% reduction in nuclear and cell volume. It appears, however, the pancreatic acinar cells of the iv fed rats maintain an adequate store of zymogen and at the same time show morphological evidences of lower synthetic activity. The findings suggest that total iv feeding may be of benefit in the treatment of pancreatic disease or trauma by relieving the acinar cells of their normal function, thus allowing the healing process to take place in the pancreas of a patient who is receiving adequate nutrition.

Original languageEnglish (US)
Pages (from-to)267-276
Number of pages10
JournalJournal of Surgical Research
Volume19
Issue number4
DOIs
StatePublished - Oct 1975
Externally publishedYes

ASJC Scopus subject areas

  • Surgery

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