Morphine: Conditioned increases in self-administration in rhesus monkeys

Stephen R. Goldberg, James H. Woods, Charles R. Schuster

Research output: Contribution to journalArticlepeer-review

72 Scopus citations

Abstract

Operant responding in three monkeys was maintained by intravenous presentations of morphine. Nalorphine produced reliable increases in morphine-reinforced responding. With successive daily nalorphine injections there was a decreased latency of self-administration responding for morphine, and substituted saline injections produced conditioned increases in morphine-reinforced responding.

Original languageEnglish (US)
Pages (from-to)1306-1307
Number of pages2
JournalScience
Volume166
Issue number3910
DOIs
StatePublished - 1969
Externally publishedYes

ASJC Scopus subject areas

  • General

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