Monocytes and Macrophages: A Fresh Look at Functional and Phenotypic Diversity

Reto Asmis

Research output: Contribution to journalReview article

Abstract

This Forum addresses the functional and phenotypical diversity of monocytes and macrophages and explores new mechanisms that contribute to the plasticity of these cells. The contributors provide in-depth and comprehensive overviews on selected key mechanisms underlying macrophage plasticity and diversity and how they related to human disease and aging. What emerges from these contributions is the importance of the interactions of macrophages with their dynamic microenvironment and the need for a better mechanistic understanding of how these cells sense environmental cues, integrate and respond to these signals, and thereby themselves help shape their microenvironment. Antioxid. Redox Signal. 25, 756-757.

Original languageEnglish (US)
Pages (from-to)756-757
Number of pages2
JournalAntioxidants and Redox Signaling
Volume25
Issue number14
DOIs
StatePublished - Nov 10 2016

Keywords

  • aging
  • cancer
  • epigenetics
  • macrophage
  • macrophage plasticity
  • redox signaling

ASJC Scopus subject areas

  • Biochemistry
  • Physiology
  • Molecular Biology
  • Clinical Biochemistry
  • Cell Biology

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