Monoclonal antibodies developed against Botryllus blood cell antigens bind to cells of distinct lineages during embryonic development

J. M. Schlumpberger, I. L. Weissman, V. L. Scofield

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Monoclonal antibodies that bind to adult Botryllus blood cell surface antigens were used to detect and localize identical or cross‐reacting antigenic determinants on Botryllus embryonic cells. These anti‐Botryllus monoclonal reagents could be divided into three categories: 1) those that bound to most embryonic cell types, including all very early embryonic cells; 2) those that bound only to embryonic blood cells and a few other embryonic cell types; and 3) those that did not bind detectably to any embryonic cells.

Original languageEnglish (US)
Pages (from-to)205-213
Number of pages9
JournalJournal of Experimental Zoology
Volume229
Issue number2
DOIs
StatePublished - 1984
Externally publishedYes

ASJC Scopus subject areas

  • Animal Science and Zoology

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