Diversidad filogenética del hongo mucoral emergente Apophysomyces: Propuesta de tres nuevas especies.

Translated title of the contribution: Molecular phylogenetic diversity of the emerging mucoralean fungus Apophysomyces: Proposal of three new species

Eduardo Alvarez, Alberto M. Stchigel, Josep Cano, Deanna A. Sutton, Annette W. Fothergill, Jagdish Chander, Valentina Salas, Michael G. Rinaldi, Josep Guarro

Research output: Contribution to journalArticlepeer-review

58 Scopus citations

Abstract

Background: Apophysomyces is a monotypic genus belonging to the order Mucorales. The species Apophysomyces elegans has been reported to cause severe infections in immunocompromised and immunocompetent people. In a previous study of Álvarez et al.3 [J Clin Microbiol 2009;47:1650-6], we demonstrated a high variability among the 5.8S rRNA gene sequences of clinical strains of A. elegans. Material and methods: We performed a polyphasic study based on the analysis of the sequences of the histone 3 gene, the internal transcribed spacer region of the rDNA gene, and domains D1 and D2 of the 28S rRNA gene, as well as by evaluation of some relevant morphological and physiological characteristics of a set of clinical and environmental strains of A. elegans. Results and conclusions: We have demonstrated that A. elegans is a complex of species. We propose as new species. Apophysomyces ossiformis, characterised by bone-shaped sporangiospores, Apophysomyces trapeziformis, with trapezoid-shaped sporangiospores, and Apophysomyces variabilis, with variable-shaped sporangiospores. These species failed to assimilate esculin. , whereas A. elegans was able to assimilate that glycoside. Amphotericin B and posaconazole are the most active in vitro drugs against Apophysomyces.

Translated title of the contributionMolecular phylogenetic diversity of the emerging mucoralean fungus Apophysomyces: Proposal of three new species
Original languageSpanish
Pages (from-to)80-89
Number of pages10
JournalRevista Iberoamericana de Micologia
Volume27
Issue number2
DOIs
StatePublished - Apr 2010

Keywords

  • Apophysomyces elegans
  • Apophysomyces ossiformis
  • Apophysomyces trapeziformis
  • Apophysomyces variabilis
  • Phylogeny
  • Taxonomy
  • Zygomycetes

ASJC Scopus subject areas

  • Microbiology
  • Infectious Diseases

Fingerprint Dive into the research topics of 'Molecular phylogenetic diversity of the emerging mucoralean fungus Apophysomyces: Proposal of three new species'. Together they form a unique fingerprint.

Cite this