Pericentric inversions occur at a frequency of 0.12-0.7% in humans. However, pericentric inversions of chromosome 22 appear to be common, especially in patients originating from the Guadalajara region of Mexico. Here, we report a seventh case of a pericentric inversion of chromosome 22, the resulting recombinant chromosome, and describe the phenotypic features associated with such a recombinant chromosome. It is interesting that five of the seven patients with inv(22) come from Mexico, and four of the five patients from the Guadalajara region.
|Original language||English (US)|
|Number of pages||4|
|Journal||American Journal of Medical Genetics|
|State||Published - Jan 1 2004|
- Distal 22q trisomy
- Pericentric inversion
ASJC Scopus subject areas