Molecular characterization of Mycoplasma genitalium species-specific and cross-reactive determinants: identification of an immunodominant protein of M. genitalium.

J. Morrison-Plummer, D. H. Jones, K. Daly, J. G. Tully, D. Taylor-Robinson, J. B. Baseman

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

Species-specific proteins of Mycoplasma genitalium as well as proteins cross-reactive with M. pneumoniae have been identified using monoclonal antibodies generated against these mycoplasmas in enzyme-linked immunosorbent assays (ELISA) and Western blot analyses. Specificity of the antibodies was examined using M. hominis, M. orale M. salivarium and Acholeplasma laidlawii. A 140-kDa (kilodalton) protein of M. genitalium that appeared to be immunodominant in mice was also shown by radioimmunoprecipitation to be immunodominant in experimentally infected chimpanzees.

Original languageEnglish (US)
Pages (from-to)453-457
Number of pages5
JournalIsrael journal of medical sciences
Volume23
Issue number5
StatePublished - May 1987

ASJC Scopus subject areas

  • Bioengineering

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