Modified associative learning T-maze test for zebrafish (Danio rerio) and other small teleost fish

Georgianna G. Gould

Research output: Chapter in Book/Report/Conference proceedingChapter

10 Scopus citations

Abstract

Associative learning is a form of classical (Pavlovian) conditioning in which a neutral stimulus (e.g., the color green) is paired with a stimulus of some significance to an animal (e.g., food), such that for the animal, the color becomes synonymous with food to evoke the same innate, reflexive behavioral responses (e.g., food seeking). This protocol is designed to test the acquisition and extinction of reward-visual stimulus association in zebrafish (Danio rerio) in a T-maze. It is based on the visual discrimination protocol of Colwill et al. (2005), in which colors or patterns are paired with a food reward. The protocol has been modified to include a reward box within the T-maze aquarium so that the influence of drug reinforcement can be studied without the potential confound of reward residues contaminating the testing arena.

Original languageEnglish (US)
Title of host publicationZebrafish Neurobehavioral Protocols
EditorsAllan Kalueff, Jonathan Cachat
Pages61-73
Number of pages13
DOIs
StatePublished - Jan 1 2011

Publication series

NameNeuromethods
Volume51
ISSN (Print)0893-2336
ISSN (Electronic)1940-6045

Keywords

  • Classical conditioning
  • T-maze test
  • acquisition
  • extinction
  • response
  • stimulus

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Psychiatry and Mental health

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  • Cite this

    Gould, G. G. (2011). Modified associative learning T-maze test for zebrafish (Danio rerio) and other small teleost fish. In A. Kalueff, & J. Cachat (Eds.), Zebrafish Neurobehavioral Protocols (pp. 61-73). (Neuromethods; Vol. 51). https://doi.org/10.1007/978-1-60761-953-6_5