Modeling motor learning connectivity using coordinate-based meta-analysis and TMS/PET

A. R. Laird, K. Li, S. Narayana, L. R. Price, R. W. Laird, J. Xiong, P. T. Fox

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

BrainMap is a database of peak activation locations and metadata reported in functional neuroimaging studies, which was designed to develop and promote coordinate-based meta-analysis techniques. Here, we demonstrate the activation likelihood estimation (ALE) method in a meta-analysis of published TMS/PET studies. Using the results of this meta-analysis, we constructed a data-driven model of motor connectivity in TMS/PET data in which stimulation was delivered to RM1 before and after motor skill acquisition. A hybrid motor connectivity model of pre- and post-learning was generated to identify specific pathways most affected by the mechanisms involved in the motor learning process.

Original languageEnglish (US)
Title of host publicationConference Record - 43rd Asilomar Conference on Signals, Systems and Computers
Pages1079-1082
Number of pages4
DOIs
StatePublished - 2009
Event43rd Asilomar Conference on Signals, Systems and Computers - Pacific Grove, CA, United States
Duration: Nov 1 2009Nov 4 2009

Publication series

NameConference Record - Asilomar Conference on Signals, Systems and Computers
ISSN (Print)1058-6393

Other

Other43rd Asilomar Conference on Signals, Systems and Computers
Country/TerritoryUnited States
CityPacific Grove, CA
Period11/1/0911/4/09

ASJC Scopus subject areas

  • Signal Processing
  • Computer Networks and Communications

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