In vivo evaluation in humans of transport and metabolism of substrates in skeletal muscle of the forearm is important but difficult. Available approaches are briefly reviewed. In this paper we first outline a general modeling strategy to address this issue in the context of multiple tracer experiment design. A partly-flow compartmental model to assess the kinetics of glucose transport from a dual-tracer study is then presented. The effect of insulin is examined.
|Original language||English (US)|
|Number of pages||6|
|Journal||IFAC Proceedings Series|
|State||Published - Dec 1 1989|
|Event||IFAC Symposium on Modelling and Control in Biomedical Systems - Venice, Italy|
Duration: Apr 6 1988 → Apr 8 1988
ASJC Scopus subject areas