Mitochondrial acetyl-CoA carboxylase. Time course of mobilization/activation in liver of refed rats

C. R. Roman-Lopez; B. J. Shriver; C. R. Joseph; J. B. Allred

doi:10.1042/bj2600927

Mitochondrial acetyl-CoA carboxylase. Time course of mobilization/activation in liver of refed rats

C. R. Roman-Lopez, B. J. Shriver, C. R. Joseph, J. B. Allred

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Abstract

Fasted (48 h) rats were killed at 0, 2, 4, 6, 8, 12, 16, 20 and 24 h after they were refed on a high-carbohydrate diet. An increase in the maximal activity and quantity of cystolic acetyl-CoA carboxylase was found in liver of refed rats after a lag time of about 8 h. The increased quantity of cytosolic enzyme was attributable primarily to mobilization of mitochondrial storage forms and not to a substantial increase in the rate of synthesis of acetyl-CoA carboxylase.

Original language	English (US)
Pages (from-to)	927-930
Number of pages	4
Journal	Biochemical Journal
Volume	260
Issue number	3
DOIs	https://doi.org/10.1042/bj2600927
State	Published - 1989
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Cell Biology

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abstract = "Fasted (48 h) rats were killed at 0, 2, 4, 6, 8, 12, 16, 20 and 24 h after they were refed on a high-carbohydrate diet. An increase in the maximal activity and quantity of cystolic acetyl-CoA carboxylase was found in liver of refed rats after a lag time of about 8 h. The increased quantity of cytosolic enzyme was attributable primarily to mobilization of mitochondrial storage forms and not to a substantial increase in the rate of synthesis of acetyl-CoA carboxylase.",

author = "Roman-Lopez, {C. R.} and Shriver, {B. J.} and Joseph, {C. R.} and Allred, {J. B.}",

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AU - Shriver, B. J.

AU - Joseph, C. R.

AU - Allred, J. B.

PY - 1989

Y1 - 1989

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AB - Fasted (48 h) rats were killed at 0, 2, 4, 6, 8, 12, 16, 20 and 24 h after they were refed on a high-carbohydrate diet. An increase in the maximal activity and quantity of cystolic acetyl-CoA carboxylase was found in liver of refed rats after a lag time of about 8 h. The increased quantity of cytosolic enzyme was attributable primarily to mobilization of mitochondrial storage forms and not to a substantial increase in the rate of synthesis of acetyl-CoA carboxylase.

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Mitochondrial acetyl-CoA carboxylase. Time course of mobilization/activation in liver of refed rats

Abstract

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