Microbiology of burns treated with carbenicillin: Experimental and clinical observations

Robert B. Lindberg, P. William Curreri, Basil A. Pruitt

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Carbenicillin administered systemically is effective in controlling sepsis from the bum wound due to Pseudomonas in experimental animals. The flora of Pseudomonas aeruginosa in a burn ward ex­hibits a complete spectrum from sensitivity to resistance to carbenicillin. Differentiation of phage types shows that in most instances the “emergence” of resistant strains is actually colonization by a new, resistant type. At least 1 phage type of those observed appears to be moderately resistant to carbenicillin.Quantitative study of tissues from autopsy of bum patients treated with carbenicillin showed low bacterial content of the bum wound, 3 logs less than the range seen in sepsis from the bum wound. P. aeruginosa was not the predominant organism in any of 14 patients autopsied, and it was present in only 4 instances.

Original languageEnglish (US)
Pages (from-to)S34-S39
JournalJournal of Infectious Diseases
Volume122
DOIs
StatePublished - Sep 1970

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

Fingerprint Dive into the research topics of 'Microbiology of burns treated with carbenicillin: Experimental and clinical observations'. Together they form a unique fingerprint.

Cite this