Methodology for measuring cerebrovascular disease burden

Research output: Contribution to journalReview article

14 Citations (Scopus)

Abstract

Biological aging of the brain is partly attributable to aging of the cerebrovascular circulation and the effects of these vascular changes on the brain. A variety of techniques ranging from simple, clinical scores to complex radiological techniques have been used in an attempt to understand, describe and quantify this process. Simultaneously attempts have been made to relate these changes to cognitive and physical changes and the risk of dementia and stroke associated with brain aging. The most frequently used clinical scores are the Framingham Stroke Risk Profile and the Hachinski Ischemic Score for vascular dementia. Radiological techniques to estimate cerebrovascular burden include many varieties of ultrasonographic, computerized tomography (CT), magnetic resonance imaging (MRI) and nuclear medicine techniques. The radiological techniques evaluate the nature and extent of disease in the vessels supplying the brain and the pattern and extent of radiological evidence of damage to the brain both on static and dynamic imaging and are briefly outlined in this review. There are several studies using these techniques to study 'normal' aging populations, and the techniques used in the most widely known of these studies are briefly highlighted in this review.

Original languageEnglish (US)
Pages (from-to)409-422
Number of pages14
JournalInternational Review of Psychiatry
Volume18
Issue number5
DOIs
StatePublished - Oct 1 2006
Externally publishedYes

Fingerprint

Cerebrovascular Disorders
Brain
Cerebrovascular Circulation
Stroke
Vascular Dementia
Nuclear Medicine
Blood Vessels
Dementia
Tomography
Magnetic Resonance Imaging
Population

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Methodology for measuring cerebrovascular disease burden. / Seshadri, Sudha.

In: International Review of Psychiatry, Vol. 18, No. 5, 01.10.2006, p. 409-422.

Research output: Contribution to journalReview article

@article{0785dad09d1c46fc8142c277b152be02,
title = "Methodology for measuring cerebrovascular disease burden",
abstract = "Biological aging of the brain is partly attributable to aging of the cerebrovascular circulation and the effects of these vascular changes on the brain. A variety of techniques ranging from simple, clinical scores to complex radiological techniques have been used in an attempt to understand, describe and quantify this process. Simultaneously attempts have been made to relate these changes to cognitive and physical changes and the risk of dementia and stroke associated with brain aging. The most frequently used clinical scores are the Framingham Stroke Risk Profile and the Hachinski Ischemic Score for vascular dementia. Radiological techniques to estimate cerebrovascular burden include many varieties of ultrasonographic, computerized tomography (CT), magnetic resonance imaging (MRI) and nuclear medicine techniques. The radiological techniques evaluate the nature and extent of disease in the vessels supplying the brain and the pattern and extent of radiological evidence of damage to the brain both on static and dynamic imaging and are briefly outlined in this review. There are several studies using these techniques to study 'normal' aging populations, and the techniques used in the most widely known of these studies are briefly highlighted in this review.",
author = "Sudha Seshadri",
year = "2006",
month = "10",
day = "1",
doi = "10.1080/09540260600935413",
language = "English (US)",
volume = "18",
pages = "409--422",
journal = "International Review of Psychiatry",
issn = "0954-0261",
publisher = "Informa Healthcare",
number = "5",

}

TY - JOUR

T1 - Methodology for measuring cerebrovascular disease burden

AU - Seshadri, Sudha

PY - 2006/10/1

Y1 - 2006/10/1

N2 - Biological aging of the brain is partly attributable to aging of the cerebrovascular circulation and the effects of these vascular changes on the brain. A variety of techniques ranging from simple, clinical scores to complex radiological techniques have been used in an attempt to understand, describe and quantify this process. Simultaneously attempts have been made to relate these changes to cognitive and physical changes and the risk of dementia and stroke associated with brain aging. The most frequently used clinical scores are the Framingham Stroke Risk Profile and the Hachinski Ischemic Score for vascular dementia. Radiological techniques to estimate cerebrovascular burden include many varieties of ultrasonographic, computerized tomography (CT), magnetic resonance imaging (MRI) and nuclear medicine techniques. The radiological techniques evaluate the nature and extent of disease in the vessels supplying the brain and the pattern and extent of radiological evidence of damage to the brain both on static and dynamic imaging and are briefly outlined in this review. There are several studies using these techniques to study 'normal' aging populations, and the techniques used in the most widely known of these studies are briefly highlighted in this review.

AB - Biological aging of the brain is partly attributable to aging of the cerebrovascular circulation and the effects of these vascular changes on the brain. A variety of techniques ranging from simple, clinical scores to complex radiological techniques have been used in an attempt to understand, describe and quantify this process. Simultaneously attempts have been made to relate these changes to cognitive and physical changes and the risk of dementia and stroke associated with brain aging. The most frequently used clinical scores are the Framingham Stroke Risk Profile and the Hachinski Ischemic Score for vascular dementia. Radiological techniques to estimate cerebrovascular burden include many varieties of ultrasonographic, computerized tomography (CT), magnetic resonance imaging (MRI) and nuclear medicine techniques. The radiological techniques evaluate the nature and extent of disease in the vessels supplying the brain and the pattern and extent of radiological evidence of damage to the brain both on static and dynamic imaging and are briefly outlined in this review. There are several studies using these techniques to study 'normal' aging populations, and the techniques used in the most widely known of these studies are briefly highlighted in this review.

UR - http://www.scopus.com/inward/record.url?scp=33750605452&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33750605452&partnerID=8YFLogxK

U2 - 10.1080/09540260600935413

DO - 10.1080/09540260600935413

M3 - Review article

C2 - 17085360

AN - SCOPUS:33750605452

VL - 18

SP - 409

EP - 422

JO - International Review of Psychiatry

JF - International Review of Psychiatry

SN - 0954-0261

IS - 5

ER -