Methadone-induced bradycardia

Mahi Lakshmi Ashwath; Mohammad Ajjan; Talley Culclasure

doi:10.1016/j.jemermed.2004.10.022

Methadone-induced bradycardia

Mahi Lakshmi Ashwath
, Mohammad Ajjan
, Talley Culclasure

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Methadone is commonly used in opiate detoxification in high dose. It has a molecular structure similar to verapamil and has been reported to cause similar side effects with continuous high-dose infusion. We report the case of a patient with a history of addiction and abuse of alprazolam and hydrocodone who developed sinus bradycardia after being started on oral methadone for detoxification. The potential of methadone to cause side effects similar to verapamil must be considered in any patient taking methadone.

Original language	English (US)
Pages (from-to)	73-75
Number of pages	3
Journal	Journal of Emergency Medicine
Volume	29
Issue number	1
DOIs	https://doi.org/10.1016/j.jemermed.2004.10.022
State	Published - Jul 2005
Externally published	Yes

Keywords

Bradycardia
Methadone
Verapamil

ASJC Scopus subject areas

Emergency Medicine

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10.1016/j.jemermed.2004.10.022

Cite this

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title = "Methadone-induced bradycardia",

abstract = "Methadone is commonly used in opiate detoxification in high dose. It has a molecular structure similar to verapamil and has been reported to cause similar side effects with continuous high-dose infusion. We report the case of a patient with a history of addiction and abuse of alprazolam and hydrocodone who developed sinus bradycardia after being started on oral methadone for detoxification. The potential of methadone to cause side effects similar to verapamil must be considered in any patient taking methadone.",

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T1 - Methadone-induced bradycardia

AU - Ashwath, Mahi Lakshmi

AU - Ajjan, Mohammad

AU - Culclasure, Talley

PY - 2005/7

Y1 - 2005/7

N2 - Methadone is commonly used in opiate detoxification in high dose. It has a molecular structure similar to verapamil and has been reported to cause similar side effects with continuous high-dose infusion. We report the case of a patient with a history of addiction and abuse of alprazolam and hydrocodone who developed sinus bradycardia after being started on oral methadone for detoxification. The potential of methadone to cause side effects similar to verapamil must be considered in any patient taking methadone.

AB - Methadone is commonly used in opiate detoxification in high dose. It has a molecular structure similar to verapamil and has been reported to cause similar side effects with continuous high-dose infusion. We report the case of a patient with a history of addiction and abuse of alprazolam and hydrocodone who developed sinus bradycardia after being started on oral methadone for detoxification. The potential of methadone to cause side effects similar to verapamil must be considered in any patient taking methadone.

KW - Bradycardia

KW - Methadone

KW - Verapamil

UR - https://www.scopus.com/pages/publications/20444369187

UR - https://www.scopus.com/pages/publications/20444369187#tab=citedBy

U2 - 10.1016/j.jemermed.2004.10.022

DO - 10.1016/j.jemermed.2004.10.022

M3 - Article

C2 - 15961013

AN - SCOPUS:20444369187

SN - 0736-4679

VL - 29

SP - 73

EP - 75

JO - Journal of Emergency Medicine

JF - Journal of Emergency Medicine

IS - 1

ER -

Methadone-induced bradycardia

Abstract

Keywords

ASJC Scopus subject areas

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