Metal-free, efficient hydrazination of imidazo[1,2-a]pyridine with diethyl azodicarboxylate in neutral media

Yuanxiang Wang; Brendan Frett; Nick McConnell; Hong Yu Li

doi:10.1039/c4ob02284j

Metal-free, efficient hydrazination of imidazo[1,2-a]pyridine with diethyl azodicarboxylate in neutral media

Yuanxiang Wang, Brendan Frett, Nick McConnell, Hong Yu Li

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

The first example of metal-free regioselective hydrazination of imidazo[1,2-a]pyridine with diethyl azodicarboxylate is accomplished. This procedure is chemically appealing due to the high degree of functional group tolerance and efficiency in expanding the molecular diversity.

Original language	English (US)
Pages (from-to)	2958-2964
Number of pages	7
Journal	Organic and Biomolecular Chemistry
Volume	13
Issue number	10
DOIs	https://doi.org/10.1039/c4ob02284j
State	Published - Mar 14 2015
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1039/c4ob02284j

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title = "Metal-free, efficient hydrazination of imidazo[1,2-a]pyridine with diethyl azodicarboxylate in neutral media",

abstract = "The first example of metal-free regioselective hydrazination of imidazo[1,2-a]pyridine with diethyl azodicarboxylate is accomplished. This procedure is chemically appealing due to the high degree of functional group tolerance and efficiency in expanding the molecular diversity.",

author = "Yuanxiang Wang and Brendan Frett and Nick McConnell and Li, {Hong Yu}",

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AU - Wang, Yuanxiang

AU - Frett, Brendan

AU - McConnell, Nick

AU - Li, Hong Yu

PY - 2015/3/14

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AB - The first example of metal-free regioselective hydrazination of imidazo[1,2-a]pyridine with diethyl azodicarboxylate is accomplished. This procedure is chemically appealing due to the high degree of functional group tolerance and efficiency in expanding the molecular diversity.

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Metal-free, efficient hydrazination of imidazo[1,2-a]pyridine with diethyl azodicarboxylate in neutral media

Abstract

ASJC Scopus subject areas

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