Metabolic and nutritional aspects of aging

D. N. Kalu, E. J. Masoro

Research output: Contribution to journalArticlepeer-review


Although the nature of the primary aging processes has yet to be defined, the major characteristics of aging are well known. These include increased probability of dying, physiological deterioration, changes in body composition and the occurrence of age-associated disease processes. It has been shown that in rodents, at least, nutrition can modulate all of these aging characteristics and thus, by implication, the primary aging processes. The aging-metabolic interactions are complex and yet to be fully defined. Bone loss is a consequence of aging in humans. Nutrition may play a role in this loss but the extent of its contribution and its complex interplay with other factors require further definition. These factors include the endocrines (parathyroid hormone, calcitonin, Vitamin D, ovarian hormones), bone remodeling, mechanical stress and genetics.

Original languageEnglish (US)
Pages (from-to)121-126
Number of pages6
Issue number4
StatePublished - 1986
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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