Meningoencephalitis in a dog due to trichosporon montevideense

L. K. Bryan, B. F. Porter, B. L. Wickes, K. A. Spaulding, S. C. Kerwin, S. D. Lawhon

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Meningoencephalitis due to infection with Trichosporon montevideense was diagnosed in a 4-year-old dog with a brief clinical history of rapidly progressing neurological signs that culminated in a comatose state. No significant gross lesions were found at post-mortem examination. Microscopically, a few scattered areas of pyogranulomatous inflammation with a few small, non-pigmented fungal hyphae were found within the cerebrum surrounding the lateral ventricles. A Trichosporon sp. was identified through culture of the brain and species was determined via sequence analysis of the internal transcribed spacer region of the Trichosporon rRNA gene. DNA in-situ hybridization confirmed the diagnosis. This is the first reported case of Trichosporon-associated meningoencephalitis in a dog.

Original languageEnglish (US)
Pages (from-to)157-161
Number of pages5
JournalJournal of Comparative Pathology
Volume151
Issue number2-3
DOIs
StatePublished - Aug 2014

Keywords

  • Dog
  • In-situ hybridization
  • Meningoencephalitis
  • Trichosporon montevideense

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • veterinary(all)

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    Bryan, L. K., Porter, B. F., Wickes, B. L., Spaulding, K. A., Kerwin, S. C., & Lawhon, S. D. (2014). Meningoencephalitis in a dog due to trichosporon montevideense. Journal of Comparative Pathology, 151(2-3), 157-161. https://doi.org/10.1016/j.jcpa.2014.04.015