This chapter focuses on membrane proteins. The knowledge concerning the structure of intrinsic membrane proteins has greatly advanced during the past decade due to the purification and characterization of hundreds of these proteins. However, much of the information about the three-dimensional structure, size, shape, molecular weight, amino acid sequence, and amino acid composition of these proteins is scattered throughout the literature making comparisons difficult. To facilitate the study of this class of proteins, this chapter presents a list of the intrinsic membrane proteins that are purified and reviews articles or literature reports containing structural information. These proteins are divided into two categories based on the extent to which they have been characterized: (1) the proteins that have been well characterized, for example, those proteins for which a reasonably accurate structural model has been determined; and (2) the proteins, for example, that have only been purified or for which limited structural information is available.
ASJC Scopus subject areas
- Molecular Biology