Melatonin promotes superovulation in sika deer (Cervus nippon)

Liang Wang, Zhi Yong Zhuo, Wen Qing Shi, Dun Xian Tan, Chao Gao, Xiu Zhi Tian, Lu Zhang, Guang Bin Zhou, Shi En Zhu, Peng Yun, Guo Shi Liu

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

In this study, the effects of melatonin (MT) on superovulation and reproductive hormones (melatonin, follicle-stimulating hormone (FSH), luteinizing hormone (LH) and PRL) were investigated in female sika deer. Different doses (40 or 80 mg/animal) of melatonin were subcutaneously implanted into deer before the breeding season. Exogenous melatonin administration significantly elevated the serum FSH levels at the time of insemination compared with levels in control animals. During superovulation, the serum LH levels in donor sika deer reached their highest values (7.1 ± 2.04 ng/mL) at the point of insemination, compared with the baseline levels (4.98 ± 0.07 ng/mL) in control animals. This high level of LH was sustained until the day of embryo recovery. In contrast, the serum levels of PRL in the 80 mg of melatonin-treated group were significantly lower than those of control deer. The average number of corpora lutea in melatonin-treated deer was significantly higher than that of the control (p < 0.05). The average number of embryos in the deer treated with 40 mg of melatonin was higher than that of the control; however, this increase did not reach significant difference (p > 0.05), which may be related to the relatively small sample size. In addition, embryonic development in melatonin-treated groups was delayed.

Original languageEnglish (US)
Pages (from-to)12107-12118
Number of pages12
JournalInternational Journal of Molecular Sciences
Volume15
Issue number7
DOIs
StatePublished - Jul 8 2014

Fingerprint

deer
melatonin
Superovulation
Deer
Melatonin
hormones
Hormones
Luteinizing Hormone
serums
animals
Animals
Insemination
Follicle Stimulating Hormone
Serum
embryos
Corpus Luteum
Sample Size
Embryonic Development
Breeding
Embryonic Structures

Keywords

  • FSH
  • LH
  • Melatonin
  • PRL
  • Sika deer
  • Superovulation

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Spectroscopy
  • Inorganic Chemistry
  • Catalysis
  • Molecular Biology
  • Computer Science Applications
  • Medicine(all)

Cite this

Wang, L., Zhuo, Z. Y., Shi, W. Q., Tan, D. X., Gao, C., Tian, X. Z., ... Liu, G. S. (2014). Melatonin promotes superovulation in sika deer (Cervus nippon). International Journal of Molecular Sciences, 15(7), 12107-12118. https://doi.org/10.3390/ijms150712107

Melatonin promotes superovulation in sika deer (Cervus nippon). / Wang, Liang; Zhuo, Zhi Yong; Shi, Wen Qing; Tan, Dun Xian; Gao, Chao; Tian, Xiu Zhi; Zhang, Lu; Zhou, Guang Bin; Zhu, Shi En; Yun, Peng; Liu, Guo Shi.

In: International Journal of Molecular Sciences, Vol. 15, No. 7, 08.07.2014, p. 12107-12118.

Research output: Contribution to journalArticle

Wang, L, Zhuo, ZY, Shi, WQ, Tan, DX, Gao, C, Tian, XZ, Zhang, L, Zhou, GB, Zhu, SE, Yun, P & Liu, GS 2014, 'Melatonin promotes superovulation in sika deer (Cervus nippon)', International Journal of Molecular Sciences, vol. 15, no. 7, pp. 12107-12118. https://doi.org/10.3390/ijms150712107
Wang, Liang ; Zhuo, Zhi Yong ; Shi, Wen Qing ; Tan, Dun Xian ; Gao, Chao ; Tian, Xiu Zhi ; Zhang, Lu ; Zhou, Guang Bin ; Zhu, Shi En ; Yun, Peng ; Liu, Guo Shi. / Melatonin promotes superovulation in sika deer (Cervus nippon). In: International Journal of Molecular Sciences. 2014 ; Vol. 15, No. 7. pp. 12107-12118.
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