Light deprivation by blinding in female hamsters was followed by a regression of the reproductive organs, an elevation of pituitary LH concentration and a depression of pituitary prolactin levels. Pinealectomy negated almost completely the effects of light deprivation on the neuro-endocrine-reproductive axis. Weekly subcutaneous implants of a melatonin: beeswax pellet completely prevented the pineal gland from inhibiting reproductive physiology in blinded hamsters. The findings suggest that melatonin is not the pineal antigonado-trophic factor in female golden hamsters. Melatonin implanted hamsters also had higher than normal levels of plasma prolactin.
|Original language||English (US)|
|Number of pages||4|
|Journal||Proceedings of the Society for Experimental Biology and Medicine|
|Publication status||Published - May 1975|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)