Melatonin-Pineal Relationships in Female Golden Hamsters

R. J. Reiter, M. K. Vaughan, P. K. Rudeen, G. M. Vaughan, P. J. Waring

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


Light deprivation by blinding in female hamsters was followed by a regression of the reproductive organs, an elevation of pituitary LH concentration and a depression of pituitary prolactin levels. Pinealectomy negated almost completely the effects of light deprivation on the neuro-endocrine-reproductive axis. Weekly subcutaneous implants of a melatonin: beeswax pellet completely prevented the pineal gland from inhibiting reproductive physiology in blinded hamsters. The findings suggest that melatonin is not the pineal antigonado-trophic factor in female golden hamsters. Melatonin implanted hamsters also had higher than normal levels of plasma prolactin.

Original languageEnglish (US)
Pages (from-to)290-293
Number of pages4
JournalProceedings of the Society for Experimental Biology and Medicine
Issue number1
StatePublished - May 1975

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology


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