Melatonin

Lowering the high price of free radicals

Research output: Contribution to journalArticle

254 Citations (Scopus)

Abstract

The endogenous antioxidative defense system reduces molecular toxicity of oxygen and nitrogen-based reactive species. Melatonin is an efficient direct and indirect antioxidant. It detoxifies the highly reactive hydroxyl radical and neutralizes other toxic species, including singlet oxygen, hydrogen peroxide, nitric oxide, and peroxynitrite anion, and stimulates several antioxidative enzymes.

Original languageEnglish (US)
Pages (from-to)246-250
Number of pages5
JournalNews in Physiological Sciences
Volume15
Issue number5
StatePublished - Oct 2000

Fingerprint

Reactive Nitrogen Species
Singlet Oxygen
Peroxynitrous Acid
Poisons
Melatonin
Hydroxyl Radical
Hydrogen Peroxide
Free Radicals
Anions
Nitric Oxide
Antioxidants
Oxygen
Enzymes

ASJC Scopus subject areas

  • Physiology

Cite this

Melatonin : Lowering the high price of free radicals. / Reiter, Russel J.

In: News in Physiological Sciences, Vol. 15, No. 5, 10.2000, p. 246-250.

Research output: Contribution to journalArticle

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