Melatonin in the lacrimal gland: First demonstration and experimental manipulation

Molina C. Mhatre, Albert S. van Jaarsveld, Russel J. Reiter

Research output: Contribution to journalArticlepeer-review

59 Scopus citations


NAT, HIOMT and melatonin are described in the extra-orbital lacrimal glands. The extra-orbital lacrimal glands of female Syrian hamsters contain higher NAT activity and melatonin levels than those in male glands, while male glands have higher HIOMT activity. Castration did not change melatonin in the lacrimal glands, although NAT and HIOMT activities were altered. The exposure of female hamsters to light in the morning (0600h) was associated with a reduction in both NAT activity and melatonin levels. Porphyrins were not detected in the lacrimal glands of either male or female hamsters.

Original languageEnglish (US)
Pages (from-to)1186-1192
Number of pages7
JournalBiochemical and Biophysical Research Communications
Issue number3
StatePublished - Jun 30 1988

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology


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