Abstract
The antioxidative properties of melatonin, structurally-related indoles and the chain-breaking antioxidants ascorbate, trolox and glutathione were investigated using the radical trapping reagent ABTS (2,2'-azino-bis-3-ethylbenz-thiazoline-6-sulphonic acid). The indole compounds and the phenolic or thiolic antioxidants acted synergistically suppressing the formation of the ABTS cation radical ABTS(*)+ completely when coincubated. Electron-donating indole compounds such as melatonin and chain-breaking antioxidants such as ascorbate can act in concert to provide potent antioxidative protection.
Original language | English (US) |
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Pages (from-to) | 87-92 |
Number of pages | 6 |
Journal | Neuroendocrinology Letters |
Volume | 17 |
Issue number | 2 |
State | Published - 1995 |
Externally published | Yes |
ASJC Scopus subject areas
- Endocrine and Autonomic Systems
- Clinical Neurology
- Neurology
- Psychiatry and Mental health
- Physiology (medical)
- Endocrinology, Diabetes and Metabolism
- Medicine (miscellaneous)