Abstract
The tumor suppressor protein BRCA2 promotes efficient repair of damaged chromosomes by homologous recombination, and it does so by influencing the activity of the Rad51 recombinase. A new biochemical study on the Ustilago maydis BRCA2 ortholog Brh2 sheds light on the molecular function of this tumor suppressor in the Rad51-mediated homologous recombination reaction.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 213-214 |
| Number of pages | 2 |
| Journal | Nature Structural and Molecular Biology |
| Volume | 12 |
| Issue number | 3 |
| DOIs | |
| State | Published - 2005 |
| Externally published | Yes |
ASJC Scopus subject areas
- Molecular Biology
- Structural Biology